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Search for: Maria Angelica Bazurto-Zapata
PURPOSE: To describe the SpO2 in wakefulness, sleep and during the apnea-hypopnea in adults living in Bogotá, located at 2640 m above sea level.
METHODS: Descriptive observational study in adults referred for polysomnogram (PSG). A normal Apnea hypopnea index (AHI) was defined as ≤ 5 and obstructive sleep apnea (OSA) was classified as mild (AHI 5-15), moderate (AHI 15-30), and severe (AHI >30). T-test or ANOVA test for SpO2 differences between groups was used.
RESULTS: 1799 patients, 33% women. 222 (12.8%) did not have OSA (normal IAH), 268 (14.9%) mild OSA, 315 (17.5%) moderate ,and 993 (55.2%) severe. In all cases a low SpO2 (SpO2<90%) was found.
The SpO2 was lower when the AHI was higher, in wakefulness, in non-REM and in REM (p< 0.001). For all grades of severity, SpO2 decreased significantly from wakefulness to non-REM sleep and to REM sleep (p<0.001). Patients with severe OSA had higher desaturation during wakefulness (85.2±6.6%), non-REM sleep (83.1±7.7%), REM sleep (78.8±10.2), and during events (75.1±9.1%).
CONCLUSIONS: Patients with OSA at 2640 m have nocturnal desaturation lower than 88%, which decreases with higher severity of OSA. The clinical impact of sleep disorders at this point may be greater than at sea level and should be studied.
Keywords: Sleep apnea, High altitude, Oxygen saturation
Objectives:To determine the sleep-disordered breathing in patients with decompensated HF
(DHF) at an altitude of 2640m. Conclusions:At an altitude of 2640m all patients with DHF presented sleep apnea, most
were severe, with CSA and a significant percentage of CSR that was
associated with higher oxygen desaturation.
Keywords: Heart Failure; Sleep Apnea; Central Apnea; Cheyne-Stokes Respiration; Altitude